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04-Oct-2019 13:55

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She was 30 when she entered Hornell High School as a geometry and pre-calculus teacher.

She took note of the struggle math posed for many of her students and incorporated unorthodox approaches (she recalls showing the movie “Donald in Mathmagic Land”) and beginning each morning with a favorite saying displayed on the corner of her blackboard.

Since small non-coding RNAs (including micro RNAs) are implicated in the regulation of gene expression, we hypothesised that longevity of centenarians may reflect alterations in small non-coding RNA expression.

We report the first comparison of micro RNAs expression profiles in mononuclear cells from centenarians, octogenarians and young individuals resident near Valencia, Spain.

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One thing led to another, and she slowly carved a career in college education.What do we take from these gutsy, old-but-not-worn pioneers?